Detection of Early-Stage Colorectal Cancer Using Cell-Free oncRNA Biomarkers and Artificial Intelligence

Our oncRNA-based blood test, powered by artificial intelligence, offers strong performance for early colorectal cancer detection, including in stage I disease for which existing blood-based assays are limited. These findings support further development toward a minimally invasive colorectal cancer screening tool.

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Publication Details

Journal
Clinical Cancer Research
Published
2025-05-14
DOI
https://doi.org/10.1158/1078-0432.ccr-25-0449
Citations
3
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
2.81
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Detection of Early-Stage Colorectal Cancer Using Cell-Free oncRNA Biomarkers and Artificial Intelligence

Lisa Fish, Fereydoun Hormozdiari, Selina Chen, Akshaya Krishnan et al.
3 citations
Clinical Cancer Research
Cancer Genomics and Diagnostics
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Detection of Early-Stage Colorectal Cancer Using Cell-Free oncRNA Biomarkers and Artificial Intelligence

Lisa Fish, Fereydoun Hormozdiari, Selina Chen, Akshaya Krishnan, Alexx J. Smith, Jeremy Ku, Babak Alipanahi, Magdalena Gębala, Babak Behsaz, Nae-Chyun Chen, Mehran Karimzadeh, Amir Momen-Roknabadi, Sandeep Sekhon, Taylor B. Cavazos, Anna Vilborg, Jieyang Wang, Lee S. Schwartzberg, Ti Lam, Martha Hernandez, Hani Goodarzi, Jennifer Yen, Helen Li, Jeff Gregg, Alice Huang, Rose Hanna, Dang Nguyen, Alex Degtiar
article en
3 citations

Abstract

Our oncRNA-based blood test, powered by artificial intelligence, offers strong performance for early colorectal cancer detection, including in stage I disease for which existing blood-based assays are limited. These findings support further development toward a minimally invasive colorectal cancer screening tool.

Clinical Cancer ResearchVol. 31(15)
University of Nevada, Reno (US), University of California, San Francisco (US), Guardant (United States) (US), Palo Alto Institute (US), California Ear Institute (US), University of California, Davis (US)
Good health and well-being
Openalex Percentile: Top 10%
Cancer Genomics and Diagnostics
2.81
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