Silencing ZIC5 suppresses glycolysis and promotes disulfidptosis in lung adenocarcinoma cells
ZIC5 plays a crucial role in promoting LUAD cell proliferation and energy metabolism while inhibiting disulfidptosis. Silencing ZIC5 markedly suppresses these processes, indicating its potential as a therapeutic target in LUAD.
Authors
- Denggao Huang (ORCID: https://orcid.org/0000-0002-9927-1622)
- Zeng CiMei
- Ximiao Ma
- Haimei Liang
- Lei Wang (ORCID: https://orcid.org/0000-0002-8811-8489)
Institutions
- Central South University (CN)
Publication Details
- Journal
- Cancer Biology & Therapy
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1080/15384047.2025.2501780
- Citations
- 5
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 4.68