Rasal2 inhibits autophagic-exosomes secretion via regulating Rab27a in triple-negative breast cancer progression
Collectively, these findings delineated the role of Rab27a in TNBC progression modulated by Rasal2 through autophagy-exos pathway and suggested that it is of great significance for the early diagnosis, targeted therapy and prognosis judgement of TNBC from the perspective of tumor microenvironment.
Authors
- Xiaojing Tang (ORCID: https://orcid.org/0000-0001-6057-4645)
- Kunning Yang (ORCID: https://orcid.org/0000-0003-2404-1280)
- Yan Kang (ORCID: https://orcid.org/0000-0001-6233-0652)
- Xuan Wang (ORCID: https://orcid.org/0000-0001-6875-566X)
- Linlin Ma (ORCID: https://orcid.org/0000-0002-3517-1593)
- Guocui Qi
- Yantao Han
Institutions
- Qingdao University (CN)
- Weifang People's Hospital (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1186/s12967-025-06530-2
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province