Postoperative ctHPVDNA Kinetics in Patients With HPV-Related Oropharyngeal Cancer
In this study, ctHPVDNA detectability early after surgery did not predict detectability at 2 weeks after surgery. ctHPVDNA clearance early after surgery could predict a negative test at 2 weeks. A negative blood draw finding on postoperative day 1 may be used to omit a postoperative blood draw at 2 weeks for minimal residual disease detection in future clinical trials.
Authors
- Linda X. Yin (ORCID: https://orcid.org/0000-0001-8515-2051)
- Danielle E. Hunter
- Eric J. Moore (ORCID: https://orcid.org/0000-0003-1103-6212)
- Kathryn M. Van Abel (ORCID: https://orcid.org/0000-0003-0513-4203)
- David M. Routman (ORCID: https://orcid.org/0000-0002-2768-003X)
- J. Daniel (ORCID: https://orcid.org/0000-0002-2957-4687)
- Kathleen R. Bartemes (ORCID: https://orcid.org/0000-0003-4561-3233)
- Aaron Bogan
- Harry E. Fuentes Bayne
- Kendall K. Tasche (ORCID: https://orcid.org/0000-0002-5913-1721)
- Patrick W. McGarrah (ORCID: https://orcid.org/0000-0002-0664-9447)
- M.A. Neben-Wittich
- Scott C. Lester (ORCID: https://orcid.org/0000-0001-5264-9811)
- Daniel L. Price (ORCID: https://orcid.org/0000-0003-3398-0562)
- C. Hidalgo (ORCID: https://orcid.org/0009-0002-6646-6260)
- Katharine A. Price
Institutions
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- JAMA Otolaryngology–Head & Neck Surgery
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1001/jamaoto.2025.1606
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85