The gut microbiome and metabolome in children with a first febrile urinary tract infection: a pilot study
This study demonstrates that gut microbiome changes are associated with the onset of fUTI in children. Machine learning models identified Shannon index, specific bacterial taxa, and breastfeeding as strong predictors of fUTI. The study highlighted the potential role of the gut microbiome in preventing fUTI.
Authors
- Viktor Bielik (ORCID: https://orcid.org/0000-0001-9525-4983)
- Patrik Konopásek (ORCID: https://orcid.org/0000-0001-6663-4020)
- Jakub Zieg (ORCID: https://orcid.org/0000-0001-6077-9536)
- Paul J. Planet (ORCID: https://orcid.org/0000-0003-0543-0539)
- Eva Baranovičová (ORCID: https://orcid.org/0000-0003-1357-9368)
- Ivan Hric
- Barbora Piteková (ORCID: https://orcid.org/0000-0002-8765-9179)
- Jakub Gécz
Institutions
- Children's Hospital of Philadelphia (US)
- Slovak Medical University (SK)
- Charles University (CZ)
- National Institute of Cardiovascular Diseases (SK)
- Biomedical Research Center of the Slovak Academy of Sciences (SK)
- University Hospital Kralovske Vinohrady (CZ)
- Comenius University Bratislava (SK)
- University of Pennsylvania (US)
Publication Details
- Journal
- Pediatric Nephrology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1007/s00467-025-06782-6
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Univerzita Komenského v Bratislave