Coronary Plaque, Inflammation, Subclinical Myocardial Injury, and Major Adverse Cardiovascular Events in the REPRIEVE Substudy
NCP and higher hs-CRP, IL-6, and hs-cTnT were associated with MACE and improved risk prediction over traditional risk factors in people with HIV without cardiac symptoms and low-to-moderate ASCVD risk. (Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults [REPRIEVE]; NCT02344290).
Authors
- Markella V. Zanni (ORCID: https://orcid.org/0000-0002-4711-3956)
- Heather J. Ribaudo (ORCID: https://orcid.org/0000-0002-0394-3990)
- Carl J. Fichtenbaum (ORCID: https://orcid.org/0000-0002-6778-7253)
- Sarah M Chu
- Júlia Karády (ORCID: https://orcid.org/0000-0002-6640-6260)
- Jana Taron (ORCID: https://orcid.org/0000-0002-1388-7531)
- Borek Foldyna (ORCID: https://orcid.org/0000-0002-2466-4827)
- Kayla Paradis
- Pamela S. Douglas (ORCID: https://orcid.org/0000-0001-9876-4049)
- Thomas Mayrhofer (ORCID: https://orcid.org/0000-0001-6287-5185)
- Steven Grinspoon (ORCID: https://orcid.org/0000-0002-6338-000X)
- Michael T. Lu (ORCID: https://orcid.org/0000-0003-4696-9610)
- Christopher R. deFilippi (ORCID: https://orcid.org/0000-0002-0660-4943)
- Carlos Malvestutto (ORCID: https://orcid.org/0000-0003-3156-2965)
- Gerald S. Bloomfield (ORCID: https://orcid.org/0000-0002-7176-1611)
- Tricia H. Burdo (ORCID: https://orcid.org/0000-0002-4224-7381)
- Marissa R Diggs
- Judith S. Currier (ORCID: https://orcid.org/0000-0003-4279-4737)
- Sara McCallum (ORCID: https://orcid.org/0000-0002-0289-1295)
- Judith A. Aberg (ORCID: https://orcid.org/0000-0001-8162-0284)
Institutions
- Rutgers, The State University of New Jersey (US)
- Harvard University (US)
- University of California, Los Angeles (US)
- Duke University (US)
- University of Mannheim (DE)
- Heidelberg University (DE)
- University Medical Center Freiburg (DE)
- University Hospital Heidelberg (DE)
- Johnson University (US)
- The Ohio State University Wexner Medical Center (US)
- Massachusetts General Hospital (US)
- Clinical Research Institute (US)
- Cancer Research And Biostatistics (US)
- Duke Institute for Health Innovation (US)
- University Medical Centre Mannheim (DE)
- University of Cincinnati Medical Center (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- JACC Advances
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1016/j.jacadv.2025.101781
- Citations
- 6
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 13.52
Funders
- National Institutes of Health