Bone Scintigraphy and Laboratory Clues to Osteomalacia in a Middle-Aged Man With Hip Fractures

A 43-year-old man with a 1-year history of bilateral hip pain, worsened by standing and walking, presented with a limping gait. x-rays showed diffuse osteoporosis (osteoblastic-lytic), and a bone scan revealed symmetric uptake in the costochondral junctions (rosary beads), femoral neck, proximal tibia, and feet, with no visualization of the kidneys, suggesting a metabolic disorder or neoplasm. Computed tomography revealed osteolytic lesions in multiple bones. Suspecting metabolic bone disease or metastasis, laboratory tests were conducted. Magnetic resonance imaging confirmed bilateral femoral neck fractures. He underwent open reduction internal fixation for the hip fractures. The imaging and laboratory findings suggest osteomalacia.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-05-14
DOI
https://doi.org/10.1097/rlu.0000000000005935
Primary Topic
Bone and Joint Diseases
Type
article
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0.00
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article

Bone Scintigraphy and Laboratory Clues to Osteomalacia in a Middle-Aged Man With Hip Fractures

Tzyy‐Ling Chuang, Yuh‐Feng Wang
Clinical Nuclear Medicine
Bone and Joint Diseases
article

Bone Scintigraphy and Laboratory Clues to Osteomalacia in a Middle-Aged Man With Hip Fractures

Tzyy‐Ling Chuang, Yuh‐Feng Wang
article en

Abstract

A 43-year-old man with a 1-year history of bilateral hip pain, worsened by standing and walking, presented with a limping gait. x-rays showed diffuse osteoporosis (osteoblastic-lytic), and a bone scan revealed symmetric uptake in the costochondral junctions (rosary beads), femoral neck, proximal tibia, and feet, with no visualization of the kidneys, suggesting a metabolic disorder or neoplasm. Computed tomography revealed osteolytic lesions in multiple bones. Suspecting metabolic bone disease or metastasis, laboratory tests were conducted. Magnetic resonance imaging confirmed bilateral femoral neck fractures. He underwent open reduction internal fixation for the hip fractures. The imaging and laboratory findings suggest osteomalacia.

Clinical Nuclear MedicineVol. 50(8)
National Yang Ming Chiao Tung University (TW), Tzu Chi University (TW), Yuanpei University (TW), Taipei Veterans General Hospital (TW)
Good health and well-being
Openalex Percentile: Top 87%
Bone and Joint Diseases
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