Hereditary Alpha-Tryptasemia Is Associated With Ongoing Symptoms in Individuals With Celiac Disease Despite Following a Gluten-free Diet
The prevalence of HαT in CeD is similar to the general population; however, all participants with CeD and HαT had ongoing gastrointestinal (GI) symptoms. Evaluation for HαT should be considered in the management of patients with CeD and persisting symptoms.
Authors
- Jonathan J. Lyons (ORCID: https://orcid.org/0000-0002-2346-8189)
- Daniel A. Leffler (ORCID: https://orcid.org/0000-0002-0750-3386)
- Michelle Galeas‐Pena (ORCID: https://orcid.org/0000-0002-9257-3222)
- Amélie Therrien (ORCID: https://orcid.org/0000-0002-6911-8598)
- Sarah Camille Glover (ORCID: https://orcid.org/0000-0002-9899-0473)
- Jocelyn A. Silvester (ORCID: https://orcid.org/0000-0002-3615-1666)
- Emma Frank
- Ciarán P. Kelly (ORCID: https://orcid.org/0000-0002-8216-1240)
- Javier Villafuerte Galvez
- Olga Pozdnyakova
- Srihitha Akula
- Lily Gillette
Institutions
- Tulane University (US)
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- La Jolla Institute for Immunology (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- University of California San Diego (US)
- University of Mississippi (US)
- VA San Diego Healthcare System (US)
- National Institute of Allergy and Infectious Diseases (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.14309/ajg.0000000000003537
- Citations
- 2
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 3.62
Funders
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases
- American College of Gastroenterology