A Case of Gastrointestinal Perforation in Guillain-Barré Syndrome

A 35-year-old man diagnosed with severe Guillain-Barr syndrome (GBS), accompanied by GalNAc-GD1a IgM antibodies, was admitted to our hospital.On the day of admisson, plasma exchange therapy was initiated.That night, he developed abdominal distention, and CT demonstrated paralytic ileus (Picture 1AB, 2AB).A gastric tube was inserted for decompression.On the 7th day after admission, he developed fever and abdominal pain.Repeat CT demonstrated free air within the abdominal cavity (Picture 3AB), suggesting gastrointestinal perforation.Therefore, emergency laparotomy was performed, and gastrointestinal perforation was confirmed.After that, his symptoms gradually improved,

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Publication Details

Journal
Internal Medicine
Published
2025-05-14
DOI
https://doi.org/10.2169/internalmedicine.5190-24
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

A Case of Gastrointestinal Perforation in Guillain-Barré Syndrome

Miki Fukazawa, Ryutaro Kimura, Kazumi Kimura, Toshiyuki Hayashi
Internal Medicine
Peripheral Neuropathies and Disorders
article

A Case of Gastrointestinal Perforation in Guillain-Barré Syndrome

Miki Fukazawa, Ryutaro Kimura, Kazumi Kimura, Toshiyuki Hayashi
article en

Abstract

A 35-year-old man diagnosed with severe Guillain-Barr syndrome (GBS), accompanied by GalNAc-GD1a IgM antibodies, was admitted to our hospital.On the day of admisson, plasma exchange therapy was initiated.That night, he developed abdominal distention, and CT demonstrated paralytic ileus (Picture 1AB, 2AB).A gastric tube was inserted for decompression.On the 7th day after admission, he developed fever and abdominal pain.Repeat CT demonstrated free air within the abdominal cavity (Picture 3AB), suggesting gastrointestinal perforation.Therefore, emergency laparotomy was performed, and gastrointestinal perforation was confirmed.After that, his symptoms gradually improved,

Internal MedicineVol. 64(22)
Nippon Medical School (JP)
Zero hunger
Openalex Percentile: Top 83%
Peripheral Neuropathies and Disorders
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