Cystatin C-derived measures of renal function as risk factors for mortality and renal replacement therapy in the critically ill – An analysis of the SWECRIT cohort
Our finding that SPS is more robustly associated with mortality in sepsis patients than in non-sepsis patients suggests that the association between SPS and mortality may depend on underlying pathophysiology. A cystatin C-based estimate of GFR is independently associated with RRT in sepsis and non-sepsis.
Authors
- Hans Friberg (ORCID: https://orcid.org/0000-0002-5588-0098)
- Peter Bentzer (ORCID: https://orcid.org/0000-0002-8783-3886)
- Anna Åkesson (ORCID: https://orcid.org/0000-0003-0204-7446)
- Anders Grubb (ORCID: https://orcid.org/0000-0002-0125-3662)
- Erik Linné (ORCID: https://orcid.org/0000-0002-5818-2498)
- Attila Frigyesi (ORCID: https://orcid.org/0000-0002-0155-4828)
- Maria Lengquist (ORCID: https://orcid.org/0000-0003-4080-396X)
- Anders Olof Larsson (ORCID: https://orcid.org/0000-0003-3161-0402)
Institutions
- Uppsala University (SE)
- Malmö University (SE)
- Lund University (SE)
- Kristianstad University (SE)
- Department of Medical Sciences (RU)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Journal of Critical Care
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1016/j.jcrc.2025.155116
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.43