Arctiin, a lignan compound, enhances adipose tissue browning and energy expenditure by activating the adenosine A2A receptor
In summary, ARC exerts protective effects against obesity by promoting the browning of white adipocytes and holds promise as a potentially beneficial therapeutic agent for the treatment of obesity.
Authors
- Yu Gu (ORCID: https://orcid.org/0000-0002-6848-4932)
- Xiaoqiu Xiao (ORCID: https://orcid.org/0000-0002-4568-8772)
- Zhuyun Wang
- Ting Luo (ORCID: https://orcid.org/0009-0008-8894-3789)
- Li Ma (ORCID: https://orcid.org/0000-0003-4677-5533)
- Wenjun He (ORCID: https://orcid.org/0000-0003-1307-3455)
- Guangcheng Qin (ORCID: https://orcid.org/0000-0003-4347-7282)
- Xiaojie Gu (ORCID: https://orcid.org/0000-0002-8187-7044)
- Xiaojing Lin
- Wenxuan Li (ORCID: https://orcid.org/0000-0002-4759-6038)
- Yi Hou (ORCID: https://orcid.org/0000-0003-0447-090X)
- Kemeng Li
- Jingshu Cai
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1186/s10020-025-01249-8
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Natural Science Foundation of China