Tetrandrine Improves Ventricular Remodeling and Inflammation via Inhibition of the MAPK/NF-κB Pathway
Taken together, these data strongly suggest that TET attenuated the Ang II-or TAC-induced ventricular remodeling, which was possibly associated with the inhibition of inflammation and activation of the MAPK/NF-κB pathway in mice. These findings suggest a novel pharmacological activity for TET in the treatment of heart failure.
Authors
- Ruoying Zhang (ORCID: https://orcid.org/0000-0001-6695-5051)
- Jinmeng Li (ORCID: https://orcid.org/0000-0002-1619-3973)
- Suhang Guo
- Yingying Xu (ORCID: https://orcid.org/0000-0003-4924-9379)
- Yuan Yuan (ORCID: https://orcid.org/0000-0002-7499-6969)
- Yu Wang (ORCID: https://orcid.org/0000-0003-1498-5210)
- Xinjun Cai (ORCID: https://orcid.org/0000-0003-3606-8819)
- Ren Zheng (ORCID: https://orcid.org/0000-0001-6928-525X)
Institutions
- Integrated Chinese Medicine (China) (HK)
- Zhejiang Hospital (CN)
Publication Details
- Journal
- International Heart Journal
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1536/ihj.24-697
- Citations
- 3
- Primary Topic
- Berberine and alkaloids research
- Type
- article
- Field-Weighted Citation Impact
- 4.18