Pathogen Diagnostic Value of Nanopore Sequencing in Postoperative Central Nervous System Infections

Compared to microbial culture and mNGS, nanopore sequencing has a higher pathogen detection rate and a lower missed diagnosis rate. In clinical practice, using nanopore sequencing as a supplement to microbial culture can aid in the diagnosis of PCNSIs.

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Publication Details

Journal
World Neurosurgery
Published
2025-05-14
DOI
https://doi.org/10.1016/j.wneu.2025.124090
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Pathogen Diagnostic Value of Nanopore Sequencing in Postoperative Central Nervous System Infections

Mu Chuanjie, Dan Xie, Yiran Liu, Wenkai Cong et al.
World Neurosurgery
Infective Endocarditis Diagnosis and Management
article

Pathogen Diagnostic Value of Nanopore Sequencing in Postoperative Central Nervous System Infections

Mu Chuanjie, Dan Xie, Yiran Liu, Wenkai Cong, Guanghong Qi
article en

Abstract

Compared to microbial culture and mNGS, nanopore sequencing has a higher pathogen detection rate and a lower missed diagnosis rate. In clinical practice, using nanopore sequencing as a supplement to microbial culture can aid in the diagnosis of PCNSIs.

World NeurosurgeryVol. 199
Aviation General Hospital (CN)
Zero hunger
Openalex Percentile: Top 84%
Infective Endocarditis Diagnosis and Management
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