Tryptophan–kynurenine metabolites associate with inflammation and immunologic phenotypes in common variable immunodeficiency
We found altered levels of several metabolites in the tryptophan-kynurenine pathway in two different CVID cohorts associated with systemic inflammation and B-cell phenotype.
Authors
- Pål Aukrust
- Mai Sasaki Aanensen Fraz (ORCID: https://orcid.org/0000-0003-2883-6240)
- Peder R. Braadland (ORCID: https://orcid.org/0000-0002-0794-7737)
- Silje F. Jørgensen (ORCID: https://orcid.org/0000-0002-0968-7051)
- Per Magne Ueland (ORCID: https://orcid.org/0000-0002-1903-0571)
- Liv Osnes
- Børre Fevang (ORCID: https://orcid.org/0000-0001-6828-0609)
- Kristian Holm (ORCID: https://orcid.org/0000-0003-4947-4365)
- Thor Ueland
- Marius Trøseid (ORCID: https://orcid.org/0000-0001-7775-3404)
- Annika E. Michelsen
- Johannes R. Hov (ORCID: https://orcid.org/0000-0002-5900-8096)
Institutions
- Oslo University Hospital (NO)
- Bevital (Norway) (NO)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1016/j.jaci.2025.04.031
- Citations
- 4
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.19
Funders
- European Research Council
- Helse Sør-Øst RHF
- H2020 European Research Council