Impact of Varicocele on Pregnancy and Live Birth Outcomes in Men with Clinical Varicocele: Systematic Review of Controlled Studies
The relationship between varicocele and conception remains contentious, primarily due to the limited number of controlled studies available for analysis. Despite an extensive systematic search for controlled studies comparing pregnancy-related outcomes in men with and without clinical varicocele, only two studies met the inclusion criteria. These studies showed no significant differences in time to achieve pregnancy or previous conception rates between the two groups. However, men with varicocele exhibited a slightly lower, statistically significant, live birth rate compared to men without varicocele. This highlights the need for further research on this topic to provide evidence-based guidance on the impact of varicocele on fertility outcomes.
Authors
- Edoardo Pescatori (ORCID: https://orcid.org/0000-0002-9326-5598)
- Т. В. Шатылко (ORCID: https://orcid.org/0000-0002-3902-9236)
- Ayad Palani (ORCID: https://orcid.org/0000-0001-7806-9903)
- Keerti Singh (ORCID: https://orcid.org/0000-0001-7532-1229)
- Ashok Agarwal (ORCID: https://orcid.org/0000-0003-0585-1026)
- Rupin Shah (ORCID: https://orcid.org/0000-0002-7868-5949)
- Dharani Moorthy (ORCID: https://orcid.org/0000-0003-2216-6901)
- Murat Dursun (ORCID: https://orcid.org/0000-0001-9115-7203)
- Widi Atmoko (ORCID: https://orcid.org/0000-0002-7793-7083)
- Shalaka S Ramgir (ORCID: https://orcid.org/0000-0001-8065-6154)
- Kareim Khalafalla (ORCID: https://orcid.org/0000-0001-9476-4869)
- Ramadan Saleh (ORCID: https://orcid.org/0000-0003-0503-3533)
- Carlo Giulioni (ORCID: https://orcid.org/0000-0001-9934-4011)
- Amarnath Rambhatla (ORCID: https://orcid.org/0000-0002-1383-6670)
- Gökhan Çeker (ORCID: https://orcid.org/0000-0002-7891-9450)
- Armand Zini (ORCID: https://orcid.org/0000-0002-2194-5578)
- Kavindra Kumar Kesari (ORCID: https://orcid.org/0000-0003-3622-9555)
- Logan Hubbard (ORCID: https://orcid.org/0000-0002-0115-6870)
- Selahi̇tti̇n Çayan (ORCID: https://orcid.org/0000-0003-4784-2208)
- Iman Shamohammadi (ORCID: https://orcid.org/0000-0002-9955-6257)
- Rossella Cannarella (ORCID: https://orcid.org/0000-0003-4599-8487)
- Raisa Galstyan (ORCID: https://orcid.org/0000-0002-9738-5087)
- Vijay Kumar (ORCID: https://orcid.org/0000-0003-3768-8104)
- Faiza Rao (ORCID: https://orcid.org/0000-0002-1054-4939)
- Archana Subarmaniuan
- Donny E. Putra
Institutions
- Chandigarh University (IN)
- University of Minnesota (US)
- Cleveland Clinic (US)
- Minneapolis Institute of Arts (US)
- Henry Ford Health System (US)
- Kurukshetra University (IN)
- Shiraz University of Medical Sciences (IR)
- Sri Ramachandra Institute of Higher Education and Research (IN)
- Symbiosis International University (IN)
- Lilavati Hospital & Research Centre (IN)
- University of Minnesota System (US)
- Kurdistan Regional Government (IQ)
- Henry Ford Hospital (US)
- University of Catania (IT)
- Sarvodaya Fertility & IVF Centre (IN)
- Global College (CY)
- Casa di Cura Columbus (IT)
- Jiangsu Institute of Metrology (CN)
- National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation (RU)
- GynePro Medical (IT)
- Erebouni Medical Center (AM)
- National Medical Research Center of Cardiology (RU)
- Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID)
- University of the West Indies (BB)
- Queen Elizabeth Hospital (BB)
- Sudan Meteorological Authority (SD)
- Hospital Bandeirantes (BR)
- İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
- Hamad Medical Corporation (QA)
- McGill University (CA)
- Mersin Üniversitesi (TR)
- Qatar University (QA)
- Istanbul University (TR)
- Michigan State University (US)
- Sohag University (EG)
Publication Details
- Journal
- The World Journal of Men s Health
- Published
- 2025-05-14
- DOI
- https://doi.org/10.5534/wjmh.250023
- Citations
- 1
- Primary Topic
- Urological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.84