<i>SPDL1</i> inhibition enhances colorectal cancer progression <i>via</i> epidermal growth factor receptor/extracellular signal-regulated kinase pathways

This study showed that the loss of SPDL1 may induce EMT and promote cell migration and invasion in CRC through the EGFR/ERK pathway.

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Publication Details

Journal
World Journal of Gastrointestinal Oncology
Published
2025-05-15
DOI
https://doi.org/10.4251/wjgo.v17.i5.104686
Citations
2
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
1.87
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article

SPDL1 inhibition enhances colorectal cancer progression via epidermal growth factor receptor/extracellular signal-regulated kinase pathways

Peng Peng, Jiean Huang, Mengbin Qin, Juan Sun et al.
2 citations
World Journal of Gastrointestinal Oncology
Cancer, Lipids, and Metabolism
1.87
article

SPDL1 inhibition enhances colorectal cancer progression via epidermal growth factor receptor/extracellular signal-regulated kinase pathways

Peng Peng, Jiean Huang, Mengbin Qin, Juan Sun, Mengshi Li, Jinxiu Zhang, Shiquan Liu, Ruo-Xi Cheng
article en
2 citations

Abstract

This study showed that the loss of SPDL1 may induce EMT and promote cell migration and invasion in CRC through the EGFR/ERK pathway.

World Journal of Gastrointestinal OncologyVol. 17(5)
Guangxi Medical University (CN)
Openalex Percentile: Top 15%
Cancer, Lipids, and Metabolism
1.87
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