Validation and analysis of key factors of Banxia Xiexin decoction against gastric cancer
Transcriptomic and proteomic analysis showed that BXD inhibited tumor growth and slowed cancer progression by suppressing five factors in the PI3K/AKT signaling pathway, including phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, phosphoinositide-3-kinase regulatory subunit 1, and AKT serine/threonine kinase 1.
Authors
- Hailiang Huang
- Tao Han (ORCID: https://orcid.org/0000-0001-6888-471X)
- Guoxiu Zu (ORCID: https://orcid.org/0000-0002-7773-0568)
- Ji-Qin Tang
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.4251/wjgo.v17.i5.104737
- Citations
- 1
- Primary Topic
- FOXO transcription factor regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.81