Homologous recombination deficiency and immunotherapy response in microsatellite-stable colorectal cancer: Evidence from a cohort study in China
This study demonstrates that CRC patients with HRD have a more favorable prognosis and suggests that HRD status could serve as a predictive marker for immunotherapy response in MSS patients.
Authors
- Liying Zhao (ORCID: https://orcid.org/0000-0002-3723-5626)
- Hao Liu (ORCID: https://orcid.org/0000-0003-1227-2954)
- Yu Jiang (ORCID: https://orcid.org/0000-0001-7036-0384)
- Zhou Xu (ORCID: https://orcid.org/0000-0002-4287-1272)
- Qingfeng Xie (ORCID: https://orcid.org/0000-0002-8692-6650)
- Haijun Deng (ORCID: https://orcid.org/0000-0003-4632-2702)
- Hao Feng (ORCID: https://orcid.org/0000-0002-7493-766X)
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.4251/wjgo.v17.i5.102767
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00