Remaining Challenges in the Treatment of Relapsed Wilms Tumor: Children's Oncology Group and International Society of Paediatric Oncology Perspectives
Wilms tumor (WT) is the most common pediatric renal tumor, and with multidisciplinary treatment overall outcomes are excellent. However, a small subset of patients with WT will relapse. The ideal treatment of relapsed WT is yet to be defined. Ongoing studies through the Children's Oncology Group Renal Tumors Committee (COG-RTC) and the International Society of Paediatric Oncology Renal Tumor Study Group (SIOP-RTSG) aim to improve risk stratification and treatment strategies. Members met at the SIOP 55th Annual Congress 2023 to outline available data and knowledge gaps and develop future research priorities.
Authors
- Amy L. Walz (ORCID: https://orcid.org/0000-0001-6235-315X)
- Jack Brzezinski (ORCID: https://orcid.org/0000-0002-9475-0077)
- Filippo Spreafico (ORCID: https://orcid.org/0000-0002-5587-3509)
- Luke Pater (ORCID: https://orcid.org/0000-0001-8297-8464)
- Norbert M. Graf (ORCID: https://orcid.org/0000-0002-2248-323X)
- Jan Godziński (ORCID: https://orcid.org/0000-0001-9687-7146)
- Marry M. van den Heuvel‐Eibrink (ORCID: https://orcid.org/0000-0002-7760-879X)
- Rhoikos Furtwängler (ORCID: https://orcid.org/0000-0002-1967-8343)
- Jesper Brok (ORCID: https://orcid.org/0000-0003-2576-0228)
- Max Pachl (ORCID: https://orcid.org/0000-0001-7228-862X)
- Justine N. van der Beek (ORCID: https://orcid.org/0000-0002-4798-8787)
- Elizabeth Anne Mullen (ORCID: https://orcid.org/0000-0002-6704-0002)
- Alissa Groenendijk (ORCID: https://orcid.org/0000-0001-6466-7785)
- Peter F. Ehrlich (ORCID: https://orcid.org/0000-0001-6161-1815)
- Andrew J. Murphy (ORCID: https://orcid.org/0000-0001-6747-0355)
- James I. Geller (ORCID: https://orcid.org/0000-0001-5181-116X)
- Geert O. Janssens (ORCID: https://orcid.org/0000-0002-0331-713X)
- Kathryn S. Sutton (ORCID: https://orcid.org/0000-0002-6451-6589)
- Marc H.W.A. Wijnen
Institutions
- Northwestern University (US)
- Cincinnati Children's Hospital Medical Center (US)
- Boston Children's Hospital (US)
- Lurie Children's Hospital (US)
- St. Jude Children's Research Hospital (US)
- Emory University (US)
- University of Toronto (CA)
- University of Washington (US)
- University of Wrocław (PL)
- University of Michigan (US)
- University Hospital of Bern (CH)
- Hospital for Sick Children (CA)
- Rigshospitalet (DK)
- University Medical Center Utrecht (NL)
- Wroclaw Medical University (PL)
- Szpital im Tadeusza Marciniaka (PL)
- Birmingham Children's Hospital (GB)
- Aflac (United States) (US)
- Dana-Farber Cancer Institute (US)
- Princess Máxima Center (NL)
- SickKids Foundation (CA)
- Children's Healthcare of Atlanta (US)
- C. S. Mott Children's Hospital (US)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Wilhelmina Children's Hospital (NL)
- University of Cincinnati (US)
- University of Birmingham (GB)
- Saarland University (DE)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1002/pbc.31790
- Citations
- 2
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- St. Baldrick's Foundation