Genetic characterization and pathogenicity of two recombinant PRRSV-2 strains from lineages 1, 3, 5, and 8 emerged in China
FJLIUY-2017 caused persistent fever, higher viremia, 20% mortality and exhibited higher pathogenicity in piglets compared to PRRSV2/CN/G8/2018. Our results suggest that recombination between different PRRSV-2 lineages can result in the development of PRRSV variants with increased pathogenicity.
Authors
- Gong Chen (ORCID: https://orcid.org/0009-0000-6477-381X)
- Yuan Yang (ORCID: https://orcid.org/0009-0004-5322-3555)
- Chunhua Wei (ORCID: https://orcid.org/0000-0001-9244-4781)
- Huijuan Dan
- Chen Liu (ORCID: https://orcid.org/0000-0002-9023-6708)
- Jiarui Li (ORCID: https://orcid.org/0000-0003-0581-5850)
- Jiankui Liu (ORCID: https://orcid.org/0000-0002-4511-4509)
- Manlin Luo (ORCID: https://orcid.org/0000-0001-6727-4338)
- Cuiqin Huang (ORCID: https://orcid.org/0000-0002-6543-5780)
- Ailing Dai (ORCID: https://orcid.org/0009-0006-3961-4239)
Institutions
- South China Agricultural University (CN)
- Longyan University (CN)
- Fujian Agriculture and Forestry University (CN)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s12917-025-04779-9
- Citations
- 7
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 8.35
Funders
- Longyan University