Is the association between visit- to- visit heart rate variability and cardiovascular disease mediated by arteriopathy as measured by carotid intima- media thickness?
HRV-VV showed a positive association with IMT, a surrogate marker for early arteriopathy. Both parameters furtherly demonstrated a synergistic impact on the likelihood of cardiovascular disease development. Given its widespread availability by continuous monitoring with wearables, HRV-VV may provide a potentially modifiable medical target for personalized cardiovascular risk stratification.
Authors
- H. Johanna
- Harriet Alexander (ORCID: https://orcid.org/0000-0003-1308-8008)
- Bernhard Hemmer (ORCID: https://orcid.org/0000-0001-5985-6784)
- Pantel Klaus
- Schmidt Georg
- Nimmrichter Bernhard
- Iván David
- Sander Dirk
- Wunderlich Silke
Institutions
- TUM Klinikum (DE)
- Munich Cluster for Systems Neurology (DE)
- Franziskus-Krankenhaus Berlin (DE)
- Institut für Versorgungsforschung in der Onkologie (DE)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108348
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00