Unraveling the role of stromal disruption in aggressive breast cancer etiology and outcomes
Our findings highlight the active stromal role in aggressive BC etiology and outcomes, opening possibilities for readily identifying high-risk women across the BC continuum that may benefit from stroma-centric preventative or therapeutic strategies.
Authors
- Nicholas Titiloye (ORCID: https://orcid.org/0000-0001-7578-5859)
- Scott M. Lawrence (ORCID: https://orcid.org/0000-0002-5297-7978)
- Alyssa Klein (ORCID: https://orcid.org/0000-0003-3763-5731)
- Lawrence Edusei (ORCID: https://orcid.org/0000-0001-5323-0502)
- Teresa M. Kimes
- Jonine D. Figueroa (ORCID: https://orcid.org/0000-0002-5100-623X)
- Mustapha Abubakar (ORCID: https://orcid.org/0000-0003-3728-6535)
- Ruth M. Pfeiffer (ORCID: https://orcid.org/0000-0001-7791-2698)
- Xiaohong R. Yang (ORCID: https://orcid.org/0000-0003-4451-8664)
- Thomas U. Ahearn (ORCID: https://orcid.org/0000-0003-0771-7752)
- Karun Mutreja (ORCID: https://orcid.org/0009-0007-0712-7257)
- Gretchen L. Gierach (ORCID: https://orcid.org/0000-0002-0165-5522)
- Jill E. Henry (ORCID: https://orcid.org/0000-0002-0998-6481)
- Máire A. Duggan (ORCID: https://orcid.org/0000-0001-6625-7683)
- Thomas E. Rohan (ORCID: https://orcid.org/0000-0001-6897-4045)
- Donald L. Weaver (ORCID: https://orcid.org/0000-0002-2065-7187)
- Hela Koka (ORCID: https://orcid.org/0000-0002-3669-9429)
- Shaoqi Fan (ORCID: https://orcid.org/0000-0001-5894-7510)
- Pamela M. Vacek (ORCID: https://orcid.org/0000-0003-4963-0049)
- Montserrat García‐Closas (ORCID: https://orcid.org/0000-0003-1033-2650)
- Kathryn Richert-Boe
- Brian L. Sprague
Institutions
- University of Vermont (US)
- Leidos (United States) (US)
- Indiana University Health (US)
- Albert Einstein College of Medicine (US)
- Susan G. Komen Breast Cancer Foundation (US)
- University of Calgary (CA)
- Komfo Anokye Teaching Hospital (GH)
- Korle Bu Teaching Hospital (GH)
- Kaiser Permanente Center for Health Research (US)
- National Cancer Institute (US)
- Cancer Genetics (United States) (US)
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center
- Leidos Biomedical Research Inc. (United States)
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- JNCI Journal of the National Cancer Institute
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1093/jnci/djaf070
- Citations
- 4
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Breast Cancer Research Foundation
- National Cancer Institute
- Division of Cancer Epidemiology and Genetics, National Cancer Institute