Multivariate genome-wide analysis of sarcopenia reveals genetic comorbidity with urological diseases
These findings unveil a shared genetic architecture between sarcopenia and urological diseases, especially BPH, with heritability enrichment in fibroblast tissue and metabolic dysfunction emerging as the significant overlapping pathway.
Authors
- Jialin Meng (ORCID: https://orcid.org/0000-0002-4622-833X)
- Wei Dai (ORCID: https://orcid.org/0000-0001-9001-8228)
- Kun Wang (ORCID: https://orcid.org/0000-0002-0631-1323)
- Tianrui Liu (ORCID: https://orcid.org/0000-0001-7091-9432)
- Ke Xu (ORCID: https://orcid.org/0000-0001-7102-8703)
- Qianjun Liang
- Chang Yin Liang (ORCID: https://orcid.org/0000-0003-2317-1323)
- Yunyun Mei (ORCID: https://orcid.org/0000-0002-0924-7451)
- Xiangyu Zhang (ORCID: https://orcid.org/0000-0002-0869-0013)
- Peng Guo
- Feixiang Yang
Institutions
- Xiamen University (CN)
- Anhui Medical University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Wuhu Fourth People Hospital (CN)
- Jiangyin People's Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- Lu'an First People's Hospital (CN)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1016/j.exger.2025.112783
- Citations
- 2
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 2.33