Prophylactic Decellularized Adipose Matrix Treatment Mitigates Development of Radiation-Induced Cutaneous Fibrosis
This study reveals the therapeutic potential of prophylactic DAM treatment to prevent formation of RIF in skin. Our findings demonstrate that injected DAM volume is largely retained following irradiation and results in overlying skin retaining histologic and biomechanical characteristics of normal nonirradiated skin.
Authors
- Charlotte E. Berry (ORCID: https://orcid.org/0000-0002-6310-5921)
- Michael T. Longaker (ORCID: https://orcid.org/0000-0003-1430-8914)
- Derrick C. Wan (ORCID: https://orcid.org/0000-0003-4666-1683)
- Lionel Kameni
- Kelly X. Huang (ORCID: https://orcid.org/0000-0001-9092-5135)
- Michelle Griffin (ORCID: https://orcid.org/0000-0002-2027-547X)
- Rahim Nazerali (ORCID: https://orcid.org/0000-0003-1579-2787)
- Camille Brenac (ORCID: https://orcid.org/0009-0007-7085-748X)
- Carter B. Kendig
- Thalia Le
Institutions
- California Institute for Regenerative Medicine (US)
- Institute for Stem Cell Biology and Regenerative Medicine (IN)
- Stanford University (US)
Publication Details
- Journal
- Annals of Plastic Surgery
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1097/sap.0000000000004359
- Citations
- 1
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 1.36