Developing IBD Outcome Effect Size Thresholds to Inform Research, Guidelines, and Clinical Decisions
This is the first study to develop a consensus on magnitude thresholds for outcomes in IBD. These thresholds have been used in the development of the 2024 British Society of Gastroenterology guidelines for the management of IBD but can and should also be used by study designers and, most importantly, by clinicians when discussing evidence with patients as part of shared decision making. Future work to validate these findings globally and with other groups, including patients, is needed.
Authors
- Morris A. Gordon (ORCID: https://orcid.org/0000-0002-1216-5158)
- Nader Shaban
- Laurent Peyrin‐Biroulet (ORCID: https://orcid.org/0000-0003-2536-6618)
- Shellie Jean Radford (ORCID: https://orcid.org/0000-0002-2226-0810)
- Fernando Magro (ORCID: https://orcid.org/0000-0003-2634-9668)
- Alessandro Armuzzi (ORCID: https://orcid.org/0000-0003-1572-0118)
- Gordon W. Moran (ORCID: https://orcid.org/0000-0002-8906-6908)
- Vassiliki Sinopoulou (ORCID: https://orcid.org/0000-0002-2831-9406)
- Sudheer Kumar Vuyyuru (ORCID: https://orcid.org/0000-0002-8281-3237)
- Vipul Jairath
Institutions
- Western University (CA)
- Humanitas University (IT)
- Inserm (FR)
- Universidade do Porto (PT)
- University of Lancashire (GB)
- London Health Sciences Centre (CA)
- Centre for Health Technology and Services Research (PT)
- Nottingham Biomedical Research Centre (GB)
- IRCCS Humanitas Research Hospital (IT)
- Nutrition-Génétique et Exposition aux Risques Environnementaux (FR)
- Université de Lorraine (FR)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1093/ibd/izaf085
- Citations
- 4
- Primary Topic
- Primary Care and Health Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 11.26