Frailty Burden and Efficacy of Initial Invasive Strategy in Chronic Coronary Disease: The <scp>ISCHEMIA</scp> Trials
Patients with chronic coronary disease with a higher frailty burden are more likely to experience greater improvements in HRQoL with initial invasive management without a higher risk of adverse clinical events. Lower baseline SAQ scores predicted greater improvement in HRQoL with initial invasive management, independent of frailty burden.
Authors
- Matthew W. Segar (ORCID: https://orcid.org/0000-0001-6100-0897)
- Alexander Postalian
- Craig D. Rubin (ORCID: https://orcid.org/0000-0003-0267-8774)
- Subhash Banerjee (ORCID: https://orcid.org/0000-0003-0863-7914)
- Dharam J. Kumbhani (ORCID: https://orcid.org/0000-0003-4321-4538)
- Ambarish Pandey (ORCID: https://orcid.org/0000-0001-9651-3836)
- Kershaw V. Patel (ORCID: https://orcid.org/0009-0006-7418-4334)
- Amgad Mentias (ORCID: https://orcid.org/0000-0001-6555-2517)
- Neil Keshvani (ORCID: https://orcid.org/0000-0001-6890-8670)
- Lajjaben Patel (ORCID: https://orcid.org/0000-0002-9037-318X)
- Ritika Dhruve (ORCID: https://orcid.org/0009-0007-9894-3910)
- Muhammad Usman (ORCID: https://orcid.org/0000-0001-9747-8892)
Institutions
- Houston Methodist (US)
- Cleveland Clinic (US)
- Baylor University Medical Center (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Journal of the American Geriatrics Society
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1111/jgs.19508
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute on Minority Health and Health Disparities