Clinical and Biological Remission With Tezepelumab: The Real‐World Response in Severe Uncontrolled Asthma

Tezepelumab led to substantial clinical improvements and clinical remission in up to 55% of T2-high patients with severe asthma. A disconnect between clinical and biological remission was observed. The long-term significance of residual T2 inflammation on tezepelumab is unknown.

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Publication Details

Journal
Allergy
Published
2025-05-14
DOI
https://doi.org/10.1111/all.16590
Citations
21
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
24.45
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article

Clinical and Biological Remission With Tezepelumab: The Real‐World Response in Severe Uncontrolled Asthma

Jessica Gates, Jaideep Dhariwal, F Haris, Mariana Fernandes et al.
21 citations
Allergy
Asthma and respiratory diseases
24.45
article

Clinical and Biological Remission With Tezepelumab: The Real‐World Response in Severe Uncontrolled Asthma

Jessica Gates, Jaideep Dhariwal, F Haris, Mariana Fernandes, Francesca Cefaloni, Paniz Khooshemehri, Cris Roxas, J Lam, David J. Jackson, G d’Ancona, Louise Thomson, Alexandra M. Nanzer, Linda K. Green
article en
21 citations

Abstract

Tezepelumab led to substantial clinical improvements and clinical remission in up to 55% of T2-high patients with severe asthma. A disconnect between clinical and biological remission was observed. The long-term significance of residual T2 inflammation on tezepelumab is unknown.

AllergyVol. 80(6)
King's College London (GB), Guy's and St Thomas' NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 0%
Asthma and respiratory diseases
24.45
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