Role of the Renin-Angiotensin System in Blood Pressure Regulation in Smooth Muscle-Specific Cullin-3 Deficient Mice
Collectively, these data are consistent with the conclusion that loss of CUL3 function enhances ANG II sensitivity by increasing TRPC6-mediated cytosolic calcium concentration flux in smooth muscle cells.
Authors
- John J. Reho (ORCID: https://orcid.org/0000-0003-0981-3027)
- Daniel Brozoski (ORCID: https://orcid.org/0009-0006-1724-9437)
- Curt D. Sigmund (ORCID: https://orcid.org/0000-0002-1453-0921)
- Daria Golosova (ORCID: https://orcid.org/0000-0002-9663-9639)
- Gaurav Kumar (ORCID: https://orcid.org/0000-0003-2075-9244)
- Kelsey K. Wackman (ORCID: https://orcid.org/0000-0002-8253-6989)
- Brian L. Lin (ORCID: https://orcid.org/0000-0003-0800-7103)
- Samuel B.R. Lawton (ORCID: https://orcid.org/0000-0003-0270-9139)
- Pablo Nakagawa (ORCID: https://orcid.org/0000-0002-1887-7367)
- Justin L. Grobe (ORCID: https://orcid.org/0000-0001-9737-0873)
- Patricia C. Muskus
- Nisita Chaihongsa
- Ko‐Ting Lu
Institutions
- Medical College of Wisconsin (US)
- Norwegian Womens Public Health Association (NO)
Publication Details
- Journal
- Hypertension
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25045
- Citations
- 2
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 2.93