Corneal Confocal Microscopy Identifies Neurodegeneration in Relation to Disease Severity and Neuropathic Symptoms in Rosacea
Rosacea affects at least 20 million people worldwide; and is characterized by erythema, papules, pustules, telangiectasia, fibrosis, and burning sensation of the facial skin (Steinhoff and Bergstresser, 2011). The underlying pathophysiology of rosacea is complex, though neurogenic inflammation is thought to play an important role and altered cutaneous sensitivity is a hallmark of rosacea (Sulk et al., 2012). Ocular rosacea may affect more than 50% of patients with rosacea and is characterized by dryness and foreign body sensation (Sinikumpu et al., 2022).
Authors
- Rayaz Ahmed Malik (ORCID: https://orcid.org/0000-0002-7188-8903)
- Martin Steinhoff (ORCID: https://orcid.org/0000-0002-7090-2187)
- Ioannis N. Petropoulos (ORCID: https://orcid.org/0000-0002-1126-7638)
- Joerg Buddenkotte (ORCID: https://orcid.org/0000-0002-2394-3269)
- Amir Hussain (ORCID: https://orcid.org/0000-0002-8080-082X)
- Anh Jochebeth (ORCID: https://orcid.org/0000-0003-2517-8772)
- Anwar Al Hammadi
- Khairunnisa Hussain
- Hanof Ahmed (ORCID: https://orcid.org/0000-0001-5152-2640)
- Aysha Al-Malki
- F. Joy
- Seena Manjooran
- Safaa Elmoh
- Noor Al Nassr
- Roudha Al Dehneem
- Hanaan Al Maslamani
Institutions
- Cornell University (US)
- Weill Cornell Medical College in Qatar (QA)
- Hamad Medical Corporation (QA)
Publication Details
- Journal
- Journal of Investigative Dermatology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1016/j.jid.2025.03.047
- Citations
- 1
- Primary Topic
- Acne and Rosacea Treatments and Effects
- Type
- article
- Field-Weighted Citation Impact
- 2.00
Funders
- Hamad Medical Corporation
- Medical Research Council