Active electropositive α-chlorine: trichloroacetonitrile as an electrophilic chlorination reagent
An inverse-electron C–Cl bond cleavage of Cl 3 CCN under basic conditions to give the chlorine cation, which was used as an unprecedented active electrophilic chlorine source for α-mono- and α-dichlorination of carbonyl compounds.
Authors
- Changming Xu (ORCID: https://orcid.org/0000-0001-9608-7013)
- Bing Zhou (ORCID: https://orcid.org/0000-0002-2981-3895)
- Lei Bai (ORCID: https://orcid.org/0009-0004-7910-7771)
Institutions
- Lanzhou Jiaotong University (CN)
- Northwest Normal University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00379b
- Primary Topic
- Oxidative Organic Chemistry Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Gansu Province