Brønsted acid enabled metal-free remote oxygenation and amidation of unstrained C–C bonds <i>via</i> 1,4-heteroaryl migration chaperoned radical-polar crossover
A Brønsted acid enabled metal-free remote functionalization of NHPI esters via 1,4-group migration chaperoned radical-polar crossover has been established, affording a variety of alcohols, ethers and amides in moderate to good yields.
Authors
- Xiaofei Xie (ORCID: https://orcid.org/0000-0003-0467-9930)
- Kang Chen (ORCID: https://orcid.org/0000-0002-6507-9464)
- Yingguang Zhu (ORCID: https://orcid.org/0000-0002-0429-6369)
- Yukun Li (ORCID: https://orcid.org/0000-0002-0530-6258)
- Yun Shi (ORCID: https://orcid.org/0000-0003-1596-6521)
- Jia Gui
Institutions
- Nanjing Agricultural University (CN)
- Jiangsu Vocational College of Medicine (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00549c
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province
- Fundamental Research Funds for the Central Universities