Antibiotics resistance patters of Pasteurella multocida isolation from cattle

This study aimed to evaluate the efficacy of multiple antibiotics, including oxytetracycline, enrofloxacin, gentamicin, ampicillin, and erythromycin, against Pasteurella multocida isolates from cattle. Antibiotic susceptibility was assessed using the disk diffusion method. The results revealed consistent sensitivity of P. multocida to enrofloxacin and gentamicin, whereas three of the five isolates remained susceptible to oxytetracycline. In contrast, all isolates exhibited resistance to erythromycin and ampicillin. Notably, Type A strains displayed higher resistance to oxytetracycline than Type B strains, potentially due to differential selective pressure. These findings underscore enrofloxacin and gentamicin as the most effective therapeutic options for hemorrhagic septicemia in cattle, given their robust antibacterial activity against P. multocida.