Measurement of the Relationship Between the OCT Signals and Blood Glucose Concentration on Hairless Rats

The number of diabetic patients is increasing worldwide, but blood glucose levels are still measured daily by diabetic patients through an invasive method. The pain of blood sampling and the process of hemostasis place a burden on diabetic patients. Based on previous research, we investigated the relationship between blood glucose levels and attenuation of interference signals of optical coherence tomography (OCT). In the experiment, we performed a blood glucose tolerance experiment using hairless rats and compared the results of blood glucose levels with the attenuation coefficient of the OCT signal. We found that the attenuation coefficient of the OCT signal tends to decrease with increasing blood glucose concentration. Furthermore, in order to improve the accuracy of the results of the experiment, we should take more OCT signals, then calculate the average of data.