Comparison of broad-spectrum anti-Pseudomonal beta-lactam antibiotics versus targeted therapy for neutropenic patients with methicillin-susceptible <i>Staphylococcus aureus</i> bloodstream infections
The safety of the utilization of methicillin-susceptible <i>Staphylococcus aureus</i> (MSSA)-targeted therapy for the treatment of MSSA bloodstream infections in the setting of neutropenia is not well studied. This single-center, retrospective cohort study of 40 patients found no significant difference in clinical outcomes between broad-spectrum anti-Pseudomonal and MSSA-targeted beta-lactam therapy.
Authors
- Erik R. Dubberke (ORCID: https://orcid.org/0000-0003-3779-2796)
- Tamara Krekel
- Miguel A. Chavez (ORCID: https://orcid.org/0000-0003-0561-6755)
- Louis Russell
- Jeff Klaus (ORCID: https://orcid.org/0000-0003-3402-1419)
Institutions
- Barnes-Jewish Hospital (US)
- Washington University in St. Louis (US)
- Jewish Hospital (US)
Publication Details
- Journal
- Antimicrobial Stewardship & Healthcare Epidemiology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1017/ash.2025.179
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00