Global existence and regularity in a three-dimensional Keller-Segel-Navier-Stokes system with indirect signal production

We consider a degenerate quasilinear Keller-Segel-Navier-Stokes system with indirect signal production$\begin{align} \left\{ \begin{array}{l} n_t+u\cdot\nabla n = \Delta n^m-\nabla\cdot( nS(x,n,v)\nabla v),\quad x\in \Omega, t>0,\\ { }{ v_{ t}+u\cdot\nabla v = \Delta v-v+w},\quad x\in \Omega, t>0,\\ { }{w_{t}+u\cdot\nabla w = \Delta w-w+n},\quad x\in \Omega, t>0,\\ u_t+\kappa(u \cdot \nabla)u+\nabla P = \Delta u+n\nabla \phi,\quad x\in \Omega, t>0,\\ \nabla\cdot u = 0,\quad x\in \Omega, t>0\\ \end{array}\right. \end{align} \quad\quad\quad (KSNF)$in a bounded domain $ \Omega\subseteq \mathbb{R}^3 $ with a smooth boundary, where $ m>0,\kappa\in \mathbb{R} $ is a given constant, $ \phi\in W^{2,\infty}(\Omega) $. Here, $ S(x,n, v) $ is a given parameter matrix on $ \Omega\times[0,\infty)^2 $ whose Frobenius norm satisfies $ |S(x,n,v)|\leq C_S(1+n)^{-\alpha} $ with $ C_S>0 $ and $ \alpha\geq0 $. It is shown that whenever $ m +\alpha> \frac{5}{4} $, for any nonnegative initial data which is sufficiently smooth, the corresponding Neumann-Neumann-Neumann-Dirichlet initial-boundary problem possesses at least one globally weak solution, and that this solution is uniformly bounded with respect to the norm in $ L^1(\Omega)\times L^2(\Omega)\times L^2(\Omega)\times L^2(\Omega; \mathbb{R}^3) $. This work improves previous results of several other authors (see Remark 1.1).

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Journal
Discrete and Continuous Dynamical Systems
Published
2025-01-01
DOI
https://doi.org/10.3934/dcds.2025061
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
0.00

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Global existence and regularity in a three-dimensional Keller-Segel-Navier-Stokes system with indirect signal production

Jiashan Zheng, Jianing Xie
Discrete and Continuous Dynamical Systems
Mathematical Biology Tumor Growth
article

Global existence and regularity in a three-dimensional Keller-Segel-Navier-Stokes system with indirect signal production

Jiashan Zheng, Jianing Xie
article en

Abstract

We consider a degenerate quasilinear Keller-Segel-Navier-Stokes system with indirect signal production$\begin{align} \left\{ \begin{array}{l} n_t+u\cdot\nabla n = \Delta n^m-\nabla\cdot( nS(x,n,v)\nabla v),\quad x\in \Omega, t>0,\\ { }{ v_{ t}+u\cdot\nabla v = \Delta v-v+w},\quad x\in \Omega, t>0,\\ { }{w_{t}+u\cdot\nabla w = \Delta w-w+n},\quad x\in \Omega, t>0,\\ u_t+\kappa(u \cdot \nabla)u+\nabla P = \Delta u+n\nabla \phi,\quad x\in \Omega, t>0,\\ \nabla\cdot u = 0,\quad x\in \Omega, t>0\\ \end{array}\right. \end{align} \quad\quad\quad (KSNF)$in a bounded domain $ \Omega\subseteq \mathbb{R}^3 $ with a smooth boundary, where $ m>0,\kappa\in \mathbb{R} $ is a given constant, $ \phi\in W^{2,\infty}(\Omega) $. Here, $ S(x,n, v) $ is a given parameter matrix on $ \Omega\times[0,\infty)^2 $ whose Frobenius norm satisfies $ |S(x,n,v)|\leq C_S(1+n)^{-\alpha} $ with $ C_S>0 $ and $ \alpha\geq0 $. It is shown that whenever $ m +\alpha> \frac{5}{4} $, for any nonnegative initial data which is sufficiently smooth, the corresponding Neumann-Neumann-Neumann-Dirichlet initial-boundary problem possesses at least one globally weak solution, and that this solution is uniformly bounded with respect to the norm in $ L^1(\Omega)\times L^2(\Omega)\times L^2(\Omega)\times L^2(\Omega; \mathbb{R}^3) $. This work improves previous results of several other authors (see Remark 1.1).

Discrete and Continuous Dynamical SystemsVol. 45(11)
Dongbei University of Finance and Economics (CN)
National Natural Science Foundation of China, Natural Science Foundation of Shandong Province
Openalex Percentile: Top 88%
Mathematical Biology Tumor Growth
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