Association of mitochondrial RNA expression levels in saliva and plasma with interferon signature gene expression and disease activity in patients with Sjögren disease
Extracellular mt-RNA burden is elevated in SjD, and mt-RNA scores effectively discriminated patients with SjD from HCs. Saliva mt-RNA levels were associated with SjD disease activity, suggesting their potential utility in disease monitoring and stratification of SjD.
Authors
- You‐Jung Ha (ORCID: https://orcid.org/0000-0001-6107-9523)
- Seunghee Cha (ORCID: https://orcid.org/0000-0003-3772-1832)
- Yun Jong Lee (ORCID: https://orcid.org/0000-0001-7615-8611)
- Doyeong Ku (ORCID: https://orcid.org/0000-0001-6037-0001)
- Yoosik Kim (ORCID: https://orcid.org/0000-0003-3064-4643)
- Se Rim Choi (ORCID: https://orcid.org/0000-0002-4625-8571)
- Joon Young Hyon (ORCID: https://orcid.org/0000-0003-3620-1536)
- Woo‐Jin Jeong (ORCID: https://orcid.org/0000-0001-8577-6964)
- Keun‐Suh Kim (ORCID: https://orcid.org/0000-0002-5986-4810)
- Eun Ha Kang (ORCID: https://orcid.org/0000-0001-9697-1159)
- Yong Seok Choi
- Jimin Yoon (ORCID: https://orcid.org/0000-0002-7010-082X)
Institutions
- Seoul National University (KR)
- Korea Advanced Institute of Science and Technology (KR)
- Seoul National University Bundang Hospital (KR)
- University of Florida (US)
Publication Details
- Journal
- RMD Open
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1136/rmdopen-2024-005166
- Citations
- 2
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 2.33