The effects of anti-PD-1 therapy on programmed death-ligand 1 expression and glucose metabolism of normal organs in patients with advanced non-small cell lung cancer

Through a dual-modality molecular imaging approach, this research provides novel insight into anti-PD-1 therapy's effects on PD-L1 expression and glucose metabolism in normal organs of NSCLC patients, demonstrating that these parameters remain stable post-treatment.

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Publication Details

Journal
BJR|Open
Published
2024-12-27
DOI
https://doi.org/10.1093/bjro/tzaf010
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00

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article

The effects of anti-PD-1 therapy on programmed death-ligand 1 expression and glucose metabolism of normal organs in patients with advanced non-small cell lung cancer

D.J. Hughes, Gary Cook, Damion Bailey, Gitasha Chand et al.
BJR|Open
Cancer Immunotherapy and Biomarkers
article

The effects of anti-PD-1 therapy on programmed death-ligand 1 expression and glucose metabolism of normal organs in patients with advanced non-small cell lung cancer

D.J. Hughes, Gary Cook, Damion Bailey, Gitasha Chand, Vicky Goh, E. Lee, Jessica Johnson, Kathryn Adamson, Matthew Severyn
article en

Abstract

Through a dual-modality molecular imaging approach, this research provides novel insight into anti-PD-1 therapy's effects on PD-L1 expression and glucose metabolism in normal organs of NSCLC patients, demonstrating that these parameters remain stable post-treatment.

BJR|OpenVol. 7(1)
King's College London (GB), Guy's and St Thomas' NHS Foundation Trust (GB), London Cancer (GB), King's College School (GB)
Cancer Research UK, King's College London, Engineering and Physical Sciences Research Council, Centre For Medical Engineering, King’s College London
Good health and well-being
Openalex Percentile: Top 57%
Cancer Immunotherapy and Biomarkers
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The effects of anti-PD-1 therapy on programmed death-ligand 1 expression and glucose metabolism of normal organs in patients with advanced non-small cell lung cancer — D.J. Hughes, Gary Cook, et al. · BJR|Open (2024) | TGRS Research Map | TGRS