Gastrointestinal Dysmotility, Autonomic Function, and Small Intestinal Bacterial Overgrowth Among People With Well-Controlled HIV

Gastrointestinal motility is altered in PWH. This study provides preliminary evidence that changes in autonomic function may influence SBTT in PWH and that prolonged SBTT may contribute to the development of SIBO. Future studies are needed to more fully elucidate the pathophysiologic links between HIV-associated AN, altered gastrointestinal motility, the gastrointestinal microbiome, chronic inflammation, and resulting morbidity and mortality among PWH.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-05-09
DOI
https://doi.org/10.1093/infdis/jiaf238
Citations
1
Primary Topic
Advanced Drug Delivery Systems
Type
article
Field-Weighted Citation Impact
0.79
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Gastrointestinal Dysmotility, Autonomic Function, and Small Intestinal Bacterial Overgrowth Among People With Well-Controlled HIV

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1 citations
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article

Gastrointestinal Dysmotility, Autonomic Function, and Small Intestinal Bacterial Overgrowth Among People With Well-Controlled HIV

Gabriela Cedillo, Mary Catherine George, Kaitlyn Coyle, Bridget R. Mueller, Gina Lee, Jessica Robinson‐Papp, Emma K. T. Benn, Maya Campbell, Niyati Neupane, Mitali Mehta, Jack Semler, Zhu Zhao
article en
1 citations

Abstract

Gastrointestinal motility is altered in PWH. This study provides preliminary evidence that changes in autonomic function may influence SBTT in PWH and that prolonged SBTT may contribute to the development of SIBO. Future studies are needed to more fully elucidate the pathophysiologic links between HIV-associated AN, altered gastrointestinal motility, the gastrointestinal microbiome, chronic inflammation, and resulting morbidity and mortality among PWH.

The Journal of Infectious DiseasesVol. 232(2)
Independent Sector (US), Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 28%
Advanced Drug Delivery Systems
0.79
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