Daily Cigarette Abstinence and Smoking Rate With Varenicline: Relationships With Treatment, Craving, and Affect During the First Week of the Quit Attempt
This study expands clinical outcomes beyond dichotomous smoking abstinence by conducting preliminary two-part latent growth models to evaluate treatment processes and barriers to cessation on both smoking probability and smoking rate. This approach provides a complementary understanding of treatment effects and predictors of outcomes. Results suggest time, treatment, craving, and affect may have differential relationships with smoking probability versus smoking rates which would not be captured in traditional modeling for clinical trial outcomes.
Authors
- Paul M. Cinciripini (ORCID: https://orcid.org/0000-0003-2877-9928)
- Jennifer Betts (ORCID: https://orcid.org/0000-0003-3943-5848)
- Tony P. George (ORCID: https://orcid.org/0000-0003-1645-9767)
- Ashley N Dowd (ORCID: https://orcid.org/0000-0001-9399-0012)
- Larry W. Hawk (ORCID: https://orcid.org/0000-0001-6593-9746)
- Rachel F. Tyndale (ORCID: https://orcid.org/0000-0003-1297-2053)
- Robert A. Schnoll (ORCID: https://orcid.org/0000-0002-4089-856X)
- Sarah Tonkin (ORCID: https://orcid.org/0000-0001-5638-4363)
- Martin C. Mahoney (ORCID: https://orcid.org/0000-0002-5069-1140)
Institutions
- Roswell Park Comprehensive Cancer Center (US)
- Centre for Addiction and Mental Health (CA)
- The University of Texas MD Anderson Cancer Center (US)
- University of Wisconsin–Madison (US)
- Medical University of South Carolina (US)
- University of Toronto (CA)
- William S. Middleton Memorial Veterans Hospital (US)
- University of Oklahoma Health Sciences Center (US)
- University at Buffalo, State University of New York (US)
- University of Pennsylvania (US)
- Philadelphia University (US)
Publication Details
- Journal
- Nicotine & Tobacco Research
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1093/ntr/ntaf095
- Primary Topic
- Smoking Behavior and Cessation
- Type
- article
- Field-Weighted Citation Impact
- 0.00