Diosgenin Ameliorates Cardiac Function following Myocardial Ischemia Through Angiogenic and Anti-Fibrotic Properties; An Experimental Study.
Diosgenin exerts cardioprotective effects against ischemia-reperfusion injury by strengthening cardiac antioxidant defense and reducing deposition of collagen fibers. It seems that the strengthening of angiogenesis in heart tissue is one of the main mechanisms of Diosgenin to increase the heart's resistance against ischemia.
Authors
- Yaser Azizi
- Ali Mohammadkhanizadeh (ORCID: https://orcid.org/0000-0002-1816-1932)
- Kamran Rakhshan (ORCID: https://orcid.org/0000-0002-3587-423X)
- Mahdi Saberi Pirouz (ORCID: https://orcid.org/0000-0001-8553-6717)
Institutions
- Iran University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22037/aaemj.v13i1.2483
- Citations
- 1
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80