Optimizing oropharyngeal swabbing techniques: the relationship between force applied and SARS-CoV-2 detection sensitivity

These findings indicate that while applying greater force during sample collection increases the number of collected cells, it does not improve the sensitivity of SARS-CoV-2 detection and can even lead to poorer results. Further research should focus on optimizing swab design to improve sample quality and the number of cells obtained.

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Publication Details

Journal
PubMed
Published
2025-03-07
DOI
https://doi.org/10.3205/dgkh000539
Primary Topic
Facial Nerve Paralysis Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Optimizing oropharyngeal swabbing techniques: the relationship between force applied and SARS-CoV-2 detection sensitivity

Paul Rahden, Yasmin Youssef, Ralf Henkelmann, Pierre Hepp et al.
PubMed
Facial Nerve Paralysis Treatment and Research
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Optimizing oropharyngeal swabbing techniques: the relationship between force applied and SARS-CoV-2 detection sensitivity

Paul Rahden, Yasmin Youssef, Ralf Henkelmann, Pierre Hepp, Peter Melcher, Corinna Pietsch, Sandra Bergs
article en

Abstract

These findings indicate that while applying greater force during sample collection increases the number of collected cells, it does not improve the sensitivity of SARS-CoV-2 detection and can even lead to poorer results. Further research should focus on optimizing swab design to improve sample quality and the number of cells obtained.

PubMedVol. 20
Helios Park-Klinikum Leipzig (DE), Leipzig University (DE), Bernhard Nocht Institute for Tropical Medicine (DE)
Openalex Percentile: Top 83%
Facial Nerve Paralysis Treatment and Research
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