[A new triterpenoid from Elephantopus scaber].
The chemical constituents of the petroleum ether extract derived from the 90% ethanol extract of Elephantopus scaber were investigated. By silica gel column chromatography, C_(18), MCI column chromatography and semi-preparative high performance liquid chromatography, ten compounds were isolated. Their structures were identified as 3β-hydroxy-6β,7β-epoxytaraxeran-14-ene(1), 3β-hydroxyolean-12-en-28-oic acid(2), D-friedoolean-14-ene-3β,7α-diol(3), 3β-hydroxy-11α-methoxyolean-12-ene(4), 3β-hydroxyolean-11,13(18)-diene(5), 11α-hydroxy-β-amyrin(6), betulinic acid(7), 3β-hydroxy-30-norlupan-20-one(8), 6-acetonylchelerythrine(9), and 4',5'-dehydrodiodictyonema A(10) by analysis of the 1D NMR, 2D NMR, MS, and IR spectral data. Among them, compound 1 was a new triterpene and other compounds except compounds 2 and 7 were isolated from this plant for the first time.
Authors
- Junjie Hao (ORCID: https://orcid.org/0000-0002-1345-8761)
- Lin Chen (ORCID: https://orcid.org/0000-0003-2905-4873)
- Zhi‐Yong Jiang (ORCID: https://orcid.org/0000-0002-1715-268X)
- Zhangfeng Ding (ORCID: https://orcid.org/0000-0002-7122-7152)
- Yu Luo (ORCID: https://orcid.org/0009-0001-3632-4993)
- Hong-Xi Xie
- Shi-Kui Xu
Institutions
- Yunnan University (CN)
- Kunming Medical University (CN)
- Yunnan Institute For Drug Abuse (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-01
- DOI
- https://doi.org/10.19540/j.cnki.cjcmm.20241216.201
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article