[Preliminary analysis of mRNA m7G modifications in human Adenocarcinoma of esophagogastric junction].
These findings suggest that mRNA m7G modification plays a significant role in the development of AEG. Furthermore, proteins as METTL1 and WDR4 may facilitate AEG progression by regulating mRNA m7G modification. These results provide valuable insights into the molecular mechanisms underlying AEG and may inform future therapeutic strategies for this malignancy.
Authors
- Yakun Lang
- S. Zhang
- Binbin Hu (ORCID: https://orcid.org/0000-0002-0443-1401)
- Ziyan Liu (ORCID: https://orcid.org/0000-0001-9191-2790)
- Xiaoyan Wang (ORCID: https://orcid.org/0000-0001-7406-5008)
- Yu Fan (ORCID: https://orcid.org/0000-0001-7420-5138)
Institutions
- Jiangsu University (CN)
- Affiliated Hospital of Jiangsu University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-02-10
- DOI
- https://doi.org/10.3760/cma.j.cn511374-20240724-00408
- Primary Topic
- RNA modifications and cancer
- Type
- article