Incidental Detection of Renal Cell Carcinoma on 18F-NOTA-Pentixather PET/CT in a Patient With Aldosterone-producing Adenoma

We report the 18 F-NOTA-pentixather PET/CT findings of aldosterone-producing adenoma (APA) coincidence with renal cell carcinoma (RCC) in a 36-year-old man. He went to the hospital for persistent hypertension and new limb numbness and weakness. CT showed a nodule in the left adrenal gland, suggestive of an adenoma. 18 F-NOTA-pentixather PET/CT showed the nodule with high NOTA-pentixather uptake. A surprisingly NOTA-pentixather-avid lesion in the right kidney was also noted. Postoperative pathology supported a diagnosis of APA of the left adrenal gland nodule, and the right kidney lesion was RCC.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-05-08
DOI
https://doi.org/10.1097/rlu.0000000000005945
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
0.00
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article

Incidental Detection of Renal Cell Carcinoma on 18F-NOTA-Pentixather PET/CT in a Patient With Aldosterone-producing Adenoma

Lijuan Feng, Wei Zhang, Hao Wang
Clinical Nuclear Medicine
Hormonal Regulation and Hypertension
article

Incidental Detection of Renal Cell Carcinoma on 18F-NOTA-Pentixather PET/CT in a Patient With Aldosterone-producing Adenoma

Lijuan Feng, Wei Zhang, Hao Wang
article en

Abstract

We report the 18 F-NOTA-pentixather PET/CT findings of aldosterone-producing adenoma (APA) coincidence with renal cell carcinoma (RCC) in a 36-year-old man. He went to the hospital for persistent hypertension and new limb numbness and weakness. CT showed a nodule in the left adrenal gland, suggestive of an adenoma. 18 F-NOTA-pentixather PET/CT showed the nodule with high NOTA-pentixather uptake. A surprisingly NOTA-pentixather-avid lesion in the right kidney was also noted. Postoperative pathology supported a diagnosis of APA of the left adrenal gland nodule, and the right kidney lesion was RCC.

Clinical Nuclear MedicineVol. 50(11)
University of Electronic Science and Technology of China (CN)
Good health and well-being
Openalex Percentile: Top 85%
Hormonal Regulation and Hypertension
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