The Burden of Antimicrobial Resistant Bacteremia in Ontario: A Population-Wide Analysis of Attributable Mortality From 110 Pathogen-Antibiotic Combinations
We found that antimicrobial resistance was associated with a 10% relative increase in the risk of mortality among patients with bacteremia, and 1.2 AMR attributable deaths per 100 000 population per year in Ontario, Canada. Comprehensive risk adjustment is necessary for understanding the impact of AMR bacteremia on patient outcomes.
Authors
- Kevin L. Schwartz (ORCID: https://orcid.org/0000-0002-3666-7005)
- Kevin Antoine Brown (ORCID: https://orcid.org/0000-0002-1483-2188)
- Derek R. MacFadden (ORCID: https://orcid.org/0000-0002-3838-1211)
- Daniel J. Fridman (ORCID: https://orcid.org/0000-0002-2516-9967)
- Nick Daneman (ORCID: https://orcid.org/0000-0001-8827-3764)
- Beate Sander (ORCID: https://orcid.org/0000-0003-2128-9133)
- Gary Garber (ORCID: https://orcid.org/0000-0001-7633-5630)
- Valerie Leung (ORCID: https://orcid.org/0000-0002-6780-5378)
- Jennie Johnstone (ORCID: https://orcid.org/0000-0002-3785-6617)
- Samir Patel (ORCID: https://orcid.org/0000-0002-3050-9129)
- Bradley J. Langford (ORCID: https://orcid.org/0000-0001-5467-6776)
Institutions
- Sunnybrook Health Science Centre (CA)
- 3M (United States) (US)
- University of Ottawa (CA)
- University of Toronto (CA)
- Toronto General Hospital (CA)
- Public Health Ontario (CA)
- Sunnybrook Hospital (CA)
- Toronto General Hospital Research Institute
- Sunnybrook Research Institute
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1093/cid/ciaf213
- Citations
- 4
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 5.05