Evaluation of Lumbar Disc Degeneration in Postmenopausal Women’s using 1.5Tesla MRI

Lumbar disc degeneration (LDD) is a major cause of chronic low back pain (LBP), particularly in postmenopausal women, due to hormonal and age-related changes. As estrogen levels decline after menopause, degenerative processes in the intervertebral discs are accelerated, leading to reduced hydration, loss of disc height, and impaired function. These changes often result in increased pain and mobility limitations. Magnetic Resonance Imaging (MRI), especially at 1.5 Tesla (1.5T), is a key diagnostic tool for assessing LDD in postmenopausal women, providing high-resolution, non-invasive images of the lumbar spine. This review highlights the role of 1.5T MRI in detecting degenerative changes, emphasizing advanced imaging techniques such as T2-weighted imaging, T2 mapping, and diffusion-weighted imaging. These methods improve diagnostic accuracy by revealing subtle changes in disc hydration and structure. The article also discusses how estrogen deficiency accelerates disc degeneration by promoting matrix degradation and inflammation. Additionally, MRI findings such as hypointense T2 signals, Modic changes, and reduced disc height are discussed as important markers in postmenopausal women. These imaging results are crucial for personalized treatment planning. In conclusion, 1.5T MRI is an essential tool for evaluating, monitoring, and managing lumbar disc degeneration in postmenopausal women, aiding in early detection and effective treatment strategies.