Thermally accelerated Heck reaction under direct mechanocatalysis using palladium milling balls
We present a direct mechanocatalytic approach for the Mizoroki-Heck coupling of aryl iodides with olefins using palladium milling balls as catalyst under elevated temperatures in a ball milling reactor. The high chemoselectivity for C(sp<sup>2</sup>)-I bonds ensures a single product when employing multi-halogenated arenes. Additionally, a one-pot Wittig olefination/Heck cross-coupling enables direct access to stilbene derivatives from aldehydes and aryl iodides without intermediate isolation.
Authors
- Suhmi Hwang (ORCID: https://orcid.org/0000-0001-8111-0719)
- Johanna Templ (ORCID: https://orcid.org/0000-0002-4353-207X)
- Lars Borchardt (ORCID: https://orcid.org/0000-0002-8778-7816)
- Tino Schwemin
- Hakan Baltaci
Institutions
- University Hospitals of the Ruhr-University of Bochum (DE)
- Ruhr University Bochum (DE)
Publication Details
- Journal
- RSC Mechanochemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5mr00032g
- Citations
- 8
- Primary Topic
- Innovative Microfluidic and Catalytic Techniques Innovation
- Type
- article
- Field-Weighted Citation Impact
- 5.39
Funders
- European Commission
- Deutscher Akademischer Austauschdienst
- Austrian Science Fund