Clinico-pathological Profile of Patients with Non-Hodgkin’s Lymphoma

Background: Non-Hodgkin’s lymphoma (NHL) is a neoplasm affecting the lymphoid tissue. It can develop fromchromosomal translocations, exposure to certain toxins, infections, or prolonged inflammation. NHL encompassesmultiple subtypes, each with distinct epidemiology, immunophenotypic characteristics, genetic profiles, clinicalpresentations, and treatment approaches.Objective: The aim of this study is to explore the clinico-pathological profileof the NHL patients. Methods: A total of 32 patients were enrolled in this study from purposively selected two tertiarycare hospitals and all necessary information was gathered using a structured questionnaire and analyzed for the findings.Results: Majority of the patients were over 40 years; males were the predominant gender; common characteristicsincluded nodal presentation, B cell histologically and diffuse large B-cell lymphoma as per immunohistochemistry,staging wise Stage II and clinical features wise neck swelling; lastly nodal engagement-wise cervical lymphadenopathyand extra-nodal involvement wise being gastrointestinal tract and lung lymphadenopathy. Conclusion: HolisticComprehensive knowledge of the disease progression and the involvement of a multidisciplinary team are crucial forthe effective care and management of patients.