Comparative Analysis of RNAs’ Delivery Systems in diabetic wound healing: Mechanisms, Applications, and Future Prospects

The role of RNA in the treatment of the diabetic foot has received increasing attention as RNA therapy has been used in a variety of ways. This article explores various delivery methods for different types of RNA, with a focus on their mechanisms, efficiency, and potential applications. Discussed encapsulation, adsorption, layer by layer assembly, covalent binding, and targeting strategies involving MiRNA, SiRNA, mRNA, and LncRNA. Analyze the advantages and disadvantages of each method in targeted delivery and release of RNA, and point out their potential in clinical applications for diabetic wound.