The Change of Antibiotic Resistance Level in <i>Escherichia coli</i> Through the Response to Kanamycin and Ampicillin

This study investigates the alterations in antibiotic resistance of Escherichia coli under kanamycin and ampicillin exposure, while validating the co-expression of resistance genes with fluorescent proteins through genetic recombination techniques. The research demonstrates an inverse relationship between antibiotic concentrations and resistance development, revealing distinct inhibitory efficiencies among different antibiotics. These findings provide experimental evidence for understanding resistance mechanisms and offer a scientific basis for developing novel antimicrobial agents.

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Publication Details

Journal
BIO Web of Conferences
Published
2025-01-01
DOI
https://doi.org/10.1051/bioconf/202517401019
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
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article

The Change of Antibiotic Resistance Level in Escherichia coli Through the Response to Kanamycin and Ampicillin

Xin Luo, Zihan Li
BIO Web of Conferences
Antibiotic Resistance in Bacteria
article

The Change of Antibiotic Resistance Level in Escherichia coli Through the Response to Kanamycin and Ampicillin

Xin Luo, Zihan Li
article en

Abstract

This study investigates the alterations in antibiotic resistance of Escherichia coli under kanamycin and ampicillin exposure, while validating the co-expression of resistance genes with fluorescent proteins through genetic recombination techniques. The research demonstrates an inverse relationship between antibiotic concentrations and resistance development, revealing distinct inhibitory efficiencies among different antibiotics. These findings provide experimental evidence for understanding resistance mechanisms and offer a scientific basis for developing novel antimicrobial agents.

BIO Web of ConferencesVol. 174
Openalex Percentile: Top 92%
Antibiotic Resistance in Bacteria
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